THE SPERM CENTROSOME DURING FERTILIZATION IN MAMMALS - IMPLICATIONS FOR FERTILITY AND REPRODUCTION

Authors
NAVARA CS SIMERLY C ZORAN S SCHATTEN G
Citation
Cs. Navara et al., THE SPERM CENTROSOME DURING FERTILIZATION IN MAMMALS - IMPLICATIONS FOR FERTILITY AND REPRODUCTION, Reproduction, fertility and development, 7(4), 1995, pp. 747-754
Citations number
31
Categorie Soggetti
Reproductive Biology","Developmental Biology
Journal title
Reproduction, fertility and development → ACNP
ISSN journal
10313613
Volume
7
Issue
4
Year of publication
1995
Pages
747 - 754
Database
ISI
SICI code
1031-3613(1995)7:4<747:TSCDFI>2.0.ZU;2-5
Abstract
This article reviews the recent discoveries that: (I) nearly all mamma ls, including humans, inherit their centrosomes from their fathers; an d (2) some sperm are ineffective in organizing the microtubules essent ial for effecting genomic union during fertilization, leading to the s peculation that these sperm have centrosome defects. In addition, the molecular dissection and reconstitution of the human sperm centrosome in vitro is presented.