J. Kristensen et al., CERVICAL CONIZATION AND PRETERM DELIVERY LOW-BIRTH-WEIGHT - A SYSTEMATIC REVIEW OF THE LITERATURE, Acta obstetricia et gynecologica Scandinavica, 72(8), 1993, pp. 640-644
Objective. Evaluate the effect of cervical conization on preterm birth
/low birth weight (LBW). Design. A systematic review of the literature
using external or internal controls. Results. The typical odds ratio
for preterm delivery in women with prior cervical conization using ext
ernal controls was 3.23 (95% confidence interval 2.29-4.55). Using int
ernal controls the typical odds ratio for LBW was 2.97 (95% confidence
interval 1.09-8.05). Using external controls the typical odds ratio f
or LBW was 2.31 (95% confidence interval 1.33-3.99). Conclusion. Women
with cervical conization are at higher risk for preterm birth than ex
ternal controls, and the surgical intervention as such is a major dete
rmining factor.