H. Kroger et al., ESTIMATION OF SPINAL BONE-DENSITY USING CONVENTIONAL MRI - COMPARISONBETWEEN MRI AND DXA IN 32 SUBJECTS, Acta orthopaedica Scandinavica, 66(6), 1995, pp. 532-534
We evaluated the usefulness of MRIT1 and T2 relaxation times in assess
ing bone mineral status. T1 and T2 relaxation times of L3 were measure
d in 16 pairs of identical twins (24 men, 8 women), aged 25-69 years.
Bone mineral density (BMD), bone mineral content (BMC) and apparent vo
lumetric bone mineral density (BMDvol) of L3 were measured from the sa
me subjects using dual x-ray absorptiometry (DXA). T2 relaxation time
correlated inversely with BMD and BMC (r-0.40 and r-0.47, respectively
), whereas a significant positive correlation between T1 relaxation ti
me and BMDvol was found (r 0.36). The measurement of T1 may give some
information on bone mineral status in clinical MRI measurements when D
XA is not available. It is possible that T1 and T2 reflect not only bo
ne density, but also other factors related to bone structure.