STEREOSELECTIVE ANNELATION REACTIONS STAR TING FROM A CYCLIC BETA-ENAMINONE - ALPHA-PYRROLIDINYLIDENACETOPHENONE

Authors
ISSARTEL V BAHAJI EH LEAL F COUQUELET J
Citation
V. Issartel et al., STEREOSELECTIVE ANNELATION REACTIONS STAR TING FROM A CYCLIC BETA-ENAMINONE - ALPHA-PYRROLIDINYLIDENACETOPHENONE, Comptes rendus de l'Academie des sciences. Serie II. Mecanique, physique, chimie, astronomie, 321(12), 1995, pp. 521-524
Citations number
13
Categorie Soggetti
Multidisciplinary Sciences
Journal title
Comptes rendus de l'Academie des sciences. Serie II. Mecanique, physique, chimie, astronomie → ACNP
ISSN journal
12518069
Volume
321
Issue
12
Year of publication
1995
Pages
521 - 524
Database
ISI
SICI code
1251-8069(1995)321:12<521:SARSTF>2.0.ZU;2-4
Abstract
alpha-pyrrolidinylidenacetophenone was prepared in two steps by reacti on of bromoacetophenone with alpha-thiopyrrolidone, followed by sulfur extrusion. The product can give rise to annelation reactions from the less stable E isomer. The structure of the obtained azabicyclic compo unds as that of the intermediate was confirmed by IR and high field NM R spectrometry. These novel bridged nitrogen heterobicyclic derivative s could be of interest in the immunopharmacological area.