SYNTHESIS AND ANTITUMOR-ACTIVITY OF RETIN OIDS WITH MODIFIED POLAR HEAD .1.

Authors
DERYABINA EL KHODONOV AA CHEREVATAYA GV KIRILLOVA YG SHVETS VI KOSTANYAN IA ASTAPOVA MV DRANITSYNA SM STAROVOITOVA EV
Citation
El. Deryabina et al., SYNTHESIS AND ANTITUMOR-ACTIVITY OF RETIN OIDS WITH MODIFIED POLAR HEAD .1., Bioorganiceskaa himia, 21(12), 1995, pp. 941-949
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Bioorganiceskaa himia → ACNP
ISSN journal
01323423
Volume
21
Issue
12
Year of publication
1995
Pages
941 - 949
Database
ISI
SICI code
0132-3423(1995)21:12<941:SAAORO>2.0.ZU;2-8
Abstract
Several retinoids with modified polar group were synthesized. Biologic al screening using HL-60 promyelocyte leukemia cells showed that the f ree carboxyl in the retinoid molecules is not the only group responsib le for exhibiting the differentiating activity.