MOLECULAR APPROACHES TO CANCER-IMMUNOTHERAPY

Authors
FORNI G CAVALLO F CONSALVO M ALLIONE A DELLABONA P CASORATI G GIOVARELLI M
Citation
G. Forni et al., MOLECULAR APPROACHES TO CANCER-IMMUNOTHERAPY, Cytokines and molecular therapy, 1(4), 1995, pp. 225-248
Citations number
205
Categorie Soggetti
Cell Biology","Medicine, Research & Experimental",Immunology,Hematology,"Biothechnology & Applied Migrobiology
Journal title
Cytokines and molecular therapy → ACNP
ISSN journal
13556568
Volume
1
Issue
4
Year of publication
1995
Pages
225 - 248
Database
ISI
SICI code
1355-6568(1995)1:4<225:MATC>2.0.ZU;2-X
Abstract
The use of cytokines and costimulatory molecule gene-engineered tumor cells to enhance tumor immunogenicity and elicit curative responses ag ainst established tumors and tumor recurrences has become an attractiv e prospect. The immunotherapy data obtained in many experimental tumor systems using these engineered cells are reviewed here to provide a r ealistic assessment of the potential and limits of this technique.