SYNTHESES AND BIOLOGICAL-ACTIVITIES OF 1- (SUBSTITUTED ISOXAZOLYL)-1,2,4-TRIAZOLES AND 1-(SUBSTITUTED PYRIMIDINYL)-1,2,4-TRIAZOLES

alpha-Oxc-alpha-(1,2,4-triazol-1-yl) ketene dithioacetals 1 reacted wi th hydroxylamine hydrochloride in the presence of barium hydrate in re fluxing ethanol to give a mixture of isomeric 1-[5-alkylthioisoxazolyl )-1,2,4-triazoles 2 and 1-(3-alkylthioisoxazolyl)-1,2,4-triazoles 2']. Their mass spectral fragmentation was discussed respectively. On trea tment with guanidine and thiourea in a refluxing sodium ethoxide, 1 af forded 1-(substituted pyrimidinyl)-1,2,4-triazoles 3 and 4. The prelim inary biological tests show that isoxazolyltriazoles 2 and 2' have pla nt-regulatory activities.