REACTIONS OF N-PHOSPHORYL SERINE AND THRE ONINE AND THEIR ESTERS CATALYZED BY IMIDAZOLE

Authors
YAN QJ YIN YW WANG Q MAO QQ ZHAO YF
Citation
Qj. Yan et al., REACTIONS OF N-PHOSPHORYL SERINE AND THRE ONINE AND THEIR ESTERS CATALYZED BY IMIDAZOLE, Gaodeng xuexiao huaxue xuebao, 16(10), 1995, pp. 1563-1566
Citations number
12
Categorie Soggetti
Chemistry
Journal title
Gaodeng xuexiao huaxue xuebao → ACNP
ISSN journal
02510790
Volume
16
Issue
10
Year of publication
1995
Pages
1563 - 1566
Database
ISI
SICI code
0251-0790(1995)16:10<1563:RONSAT>2.0.ZU;2-S
Abstract
N-phosphoryl amino acids could be catalyzed by imidazole to result in solvolysis such as ester exchanges on phosphorus, esterification, form ation of peptides and N-->O migration of the phosphoryl group. For ser ine and threonine, a phosphaoxazole product was also detected. Only N- phosphoryl serine and threonine methyl esters were catalyzed by imidaz ole, A new type of pentacoordinate phosphorus intermediate was propose d.