We describe the successful use of the short-acting, non-depolarizing n
euromuscular blocking agent, mivacurium, in a 53-yr-old female patient
with late onset congenital myopathy, undergoing elective submucous re
section of the inferior turbinates. She was unable to climb stairs and
walking was limited to periods of 15 min because of generalized weakn
ess, fatigue and shortness of breath. A Datex Relaxograph was used to
monitor the train-of-four count. No increase in sensitivity to mivacur
ium was demonstrated. A dose of 12 mg (three times the recommended ED(
95)) resulted in 88% reduction of the first of the train-of-four count
(T1) compared with control (TC). Spontaneous recovery of T1/TC to 100
% took 11 min 20 s from the time maximum block was first achieved. The
recovery index (25-75% T1/TC) was 4 min 40 s.