PROGNOSTIC FACTORS IN LOW-GRADE SUPRATENTORIAL ASTROCYTOMAS - A UNI-MULTIVARIATE STATISTICAL-ANALYSIS IN 76 SURGICALLY TREATED ADULT PATIENTS

A retrospective uni-multivariate statistical analysis was performed on 32 prognostic factors to investigate their importance in predicting s urvival in a series of 76 adult patients with low-grade supratentorial astrocytomas treated over a 13-year period. The end point used for th is study was the length of survival. The median survival time was 40 m onths. Overall actuarial survival at 2, 5, and 10 years was 69%, 38%, and 22%, respectively. Radical resection of the neoformation, a higher preoperative Karnofsky performance status (KPS) score, and an age you nger than 50 years are strongly correlated with survival; postoperativ e radiotherapy appears to be associated with increased survival only i n patients under 50 years of age.