Large-scale multisite nursing research projects require careful coordi
nation of a variety of research tasks, Many nursing studies include ca
regivers and support staff as well as patients and their significant o
thers as subjects, resulting in the need to develop and implement many
different protocols, This article presents an implementation framewor
k for multisite clinical studies incorporating the knowledge gained du
ring an investigation of patient-centered care that was conducted at 1
7 hospitals involving contact with patients, unit managers, registered
nurses, and other hospital personnel, Five areas of key research task
s are addressed: general systems design, public relations, human resou
rce issues, data quality assurances, and data management, Management o
f a multisite nursing research study, including issues related to recr
uitment and roles of project staff, training, and key research tasks,
are discussed. (C) 1996 by W.B. Saunders Company