Some cases of pneumonia can be expected to respond slowly to treatment
. For example, resolution of bacteremic pneumococcal pneumonia in an 8
5-year-old patient who smokes and has heart disease, diabetes, and mul
tilobar infiltrates is much more likely to be prolonged than is mycopl
asmal pneumonia in a 25-year-old, healthy, nonsmoking patient with a u
nilobar infiltrate. The authors describe risk factors for and causes o
f delayed resolution and present a workup strategy for cases that do n
ot respond within expected time limits.