I. Lazareth et P. Priollet, HYPERTENSIVE ISCHEMIC ULCERS - TREATEMENT WITH EARLY SPLIT SKIN-GRAFTS, Annales de dermatologie et de venereologie, 122(9), 1995, pp. 575-578
Introduction. Necrotic angiodermitis is an uncommonly hypertensive isc
hemic ulceration. It usually occurs on the legs in elderly, hypertensi
ve and sometimes diabetic patients. Its extensive and highly painful n
ature is characteristic. Currently, there is no simple effective treat
ment which is known to stop the development. We report the results of
a patch graft method applied early before the angiodermitis develops i
nto an advanced stage. Patients and methods. The technique was used in
13 consecutive patients with 16 episodes of necrotic angiodermitis. T
he graft was made 8 days (mean) after hospitalization. Results. The an
algesic effect of the graft was apparent within the first days after t
he graft. The violet halo of extension disappeared a mean of 8 days af
ter the graft. A second or even third graft was required in 8 of 16 ep
isodes. Total cicatrization was obtained after a mean delay of 33 days
. Conclusion. Patch graft is a simple, low-cost, non invasive treatmen
t which can be performed at the bedside and even in an outpatient clin
ic. This stops the extension of the necrotic angiodermitis and control
s pain. Delay to cicatrization is shorter. The favourable effect of th
e graft could possibly be mediated by vasodilator peptides liberated b
y the graft tissue which would counteract the hypothetical vasospasm.