G. Moulin et al., CLINICAL CASES - PERFORATING VERRUCIFORM COLLAGENOMA, AN EXOGENOUS INCLUSION-LINKED DERMATOSIS, Annales de dermatologie et de venereologie, 122(9), 1995, pp. 591-594
Introduction. Perforating verruciform collagenoma, first described in
1963, designates papular and keratotic post-trauma lesions which show
an aspect of epidermal perforation microscopically with large fragment
s of collagen issuing through fistulous chimneys, more or less pycnoti
c polynuclears and squamating or necrotic epidermal cells. Three publi
cations have presented this diagnosis. Case report. We observed a pati
ent with multiple lesions with macroscopic and microscopic presentatio
ns suggestive of perforating verruciform collagenoma. The lesions appe
ared after scratches and inoculation with calcium chloride. Discussion
. This case is similar to those observed after intradermal inoculation
of calcium salts. In the 4 previous cases, perforating verruciform co
llagenoma was associated with trauma allowing the intradermal penetrat
ion of a particular foreign material (glass wool, vegetable debris, dr
ugs or intravenous injections, wound caused by a metallic garbage bin)
. The exceptional nature of perforating verruciform collagenoma in hig
hly frequent skin wounds would suggest that a very particular post-tra
uma process is occurring caused by the introduction of an exogenous su
bstance within the derma: calcium chloride in our case, a non-specific
material in the four previous cases.