DUPLEX-DOPPLER ESTIMATION OF POURCELOT RESISTIVE INDEX IN ARCUATE ARTERIES OF SEDATED NORMAL CATS

Renal failure is an important cause of morbidity and mortality in feli ne patients. In human patients, intrarenal blood flow values obtained with duplex Doppler ultrasonography have been used to aid in the diagn osis and prognosis of renal failure. The purpose of this report is to present values for resistance to intrarenal blood flow in normal cats, derived by duplex Doppler ultrasonography. Ten mature clinically heal thy conditioned domestic shorthaired cats were screened for normal ren al anatomy and function by CBC, serum biochemical profile, urinalysis, urine protein/creatinine ratio, endogenous creatinine clearance, and renal B-mode ultrasonography; and for normal systemic blood pressure w ith Doppler pressure cuff measurement. Subsequently, the cats were sed ated with ketamine hydrochloride, and values for mean intrarenal (arcu ate artery) resistance to blood flow were determined by duplex Doppler ultrasonography, and expressed as the Pourcelot resistive in dex, a r atio of systolic to diastolic flow commonly used in duplex Doppler son ography in human patients. After duplex Doppler sonographic examinatio n, histological normalcy of the kidneys was verified by evaluation of ultrasound-guided percutaneous renal biopsy. Based on the obtained res istive indices, 95% confidence intervals for normal values were calcul ated as follows: left kidney, 0.52 to 0.60; right kidney, 0.55 to 0.63 . No statistically significant difference was noted between the values obtained for the right versus the left kidney. Copyright (C) 1996 by the American College of Veterinary Internal Medicine.