TRIORGANOSILICON(IV) COMPLEXES AS BIOCIDES - SYNTHETIC SPECTROSCOPIC AND BIOLOGICAL STUDIES OF N-SH AND N-OH FLUOROIMINES AND THEIR CHELATES

A facile synthesis and study of the stereochemistry and biochemical as pects of some triorganosilicon(IV) complexes derived from fluoroimines having NS and NO systems are reported. The fluoroimines were prepared by the condensation of 2-fluorobenzaldehyde and 1-(2-fluorophenyl)eth anone with semicarbazide and thiosemicarbazide. These imines react wit h triorganosilicon(IV) chlorides to yield compounds having Si-O/Si-S a nd Si<--N bonds, The structures of the compounds have been elucidated by physicochemical and spectral (UV, IR, H-1 NMR, C-13 NMR and F-9 NMR ) studies which clearly point to a trigonal bipyramidal geometry aroun d silicon(IV), as the active lone pair of nitrogen is also included in the coordination sphere. In the search for better fungicides and bact ericides, studies were conducted to assess the growth-inhibiting poten tial of the synthesized complexes against various pathogenic fungal an d bacterial strains. These studies demonstrate that the concentrations reached levels which are sufficient to inhibit and kill the pathogens .