ORGANOBORANES FOR SYNTHESIS .16. A CONVENIENT SYNTHESIS OF ENANTIOMERICALLY PURE ISOPINOCAMPHEYLAMINE, A CHIRAL DERIVATIZING AGENT FOR GAS-CHROMATOGRAPHIC ANALYSIS OF OPTICALLY-ACTIVE CARBOXYLIC-ACIDS

Authors
RAMACHANDRAN PV RANGAISHENVI MV SINGARAM B GORALSKI CT BROWN HC
Citation
Pv. Ramachandran et al., ORGANOBORANES FOR SYNTHESIS .16. A CONVENIENT SYNTHESIS OF ENANTIOMERICALLY PURE ISOPINOCAMPHEYLAMINE, A CHIRAL DERIVATIZING AGENT FOR GAS-CHROMATOGRAPHIC ANALYSIS OF OPTICALLY-ACTIVE CARBOXYLIC-ACIDS, Journal of organic chemistry, 61(1), 1996, pp. 341-345
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
61
Issue
1
Year of publication
1996
Pages
341 - 345
Database
ISI
SICI code
0022-3263(1996)61:1<341:OFS.AC>2.0.ZU;2-G
Abstract
Both isomers of enantiomerically pure isopinocampheylamine (1) have be en synthesized from the corresponding B-chlorodiisopinocampheylborane by treatment with either methylmagnesium bromide or trimethylaluminum to form B-methyldiisopinocampheylborane, followed by treatment of the intermediate with hydroxylamine-O-sulfonic acid. Application of 1 as a derivatizing agent for the gas chromatographic analysis of optically active carboxylic acids has been demonstrated.