Ams. Figueiredo et al., CHANGES IN THE SURFACE CARBOHYDRATE-COMPOSITION AND EXPOSURE OF ANIONIC GROUPS CAUSED BY BETA-LACTAM ANTIBIOTICS IN STREPTOCOCCI, Journal of antimicrobial chemotherapy, 36(6), 1995, pp. 1031-1036
Upon the addition of beta-lactam antibiotics at concentrations that ca
used a 50% reduction in the dry weight, beta-haemolytic streptococci p
roduced increased amount of rhamnose, though the hexosamine content re
mained unchanged. These sugars are components of C-carbohydrate. Siali
c acid content also increased in group B streptococcal surfaces and pe
nicillin treatment generated new accessible surface sialic acid residu
es.