THE ABSENCE OF GENETIC-MARKERS FOR STREPTOMYCIN AND RIFAMPICIN RESISTANCE IN MYCOBACTERIUM-AVIUM COMPLEX STRAINS

Authors
PORTILLOGOMEZ L NAIR J ROUSE DA MORRIS SL
Citation
L. Portillogomez et al., THE ABSENCE OF GENETIC-MARKERS FOR STREPTOMYCIN AND RIFAMPICIN RESISTANCE IN MYCOBACTERIUM-AVIUM COMPLEX STRAINS, Journal of antimicrobial chemotherapy, 36(6), 1995, pp. 1049-1053
Citations number
11
Categorie Soggetti
Microbiology,"Pharmacology & Pharmacy
Journal title
Journal of antimicrobial chemotherapy → ACNP
ISSN journal
03057453
Volume
36
Issue
6
Year of publication
1995
Pages
1049 - 1053
Database
ISI
SICI code
0305-7453(1995)36:6<1049:TAOGFS>2.0.ZU;2-I
Abstract
Mycobacterium avium, Mycobacterium intracellulare complex (MAC) bacill i are an important cause of bacteraemia in AIDS patients but treatment is complicated by their resistance to the usual antimycobacterial age nts. In this study of 20 strains of MAC none was found to have the mut ations associated with resistance to rifampicin and streptomycin in M. tuberculosis suggesting that MAC have unique mechanisms for resistanc e to these agents.