Background/Aims: A prospective study was performed to evaluate the inc
idence of bile leak after T-tube removal, using Tc-99m labelled BULIDA
scintigraphy. Patients and Methods: Thirty seven patients with choled
ocholithiasis underwent choledocholithotomy and T-tube drainage. T-tub
es were removed on. 9-26 postoperative day (mean 13.4 days). Results:
Six (16%) patients had scintigraphic evidence of bile Leak; 4 patients
had leak demonstrated in the early phase only. One patient each had p
artial persistent leak and complete bile leak. All patients were manag
ed nonsurgically; conservative treatment: (4), percutaneous drainage (
PCD) of intra-abdominal collection (1) and endoscopic sphincterotomy a
nd PCD of intraabdominal collection (1). There was no significant diff
erence in the Leak rate when T-tubes were removed at <2 weeks versus l
ater than 2 weeks (P=.97). Conclusions: T-tubes should be removed with
extreme caution and treatment of symptomatic patients should be guide
d by clinical and scintigraphic findings.