DISSEMINATED INFECTION DUE TO MYCOBACTERIUM-SCROFULACEUM IN AN IMMUNOCOMPETENT HOST

Disseminated Mycobacterium scrofulaceum infection has rarely been repo rted, and the majority of infections have been associated with AIDS or other immunocompromising diseases. We describe a previously healthy m an with M. scrofulaceum infection whose clinical manifestations includ ed miliary lung lesions, mediastinal lymphadenitis, granulomatous hepa titis, osteomyelitis, subcutaneous abscesses, and probable renal invol vement, M, scrofulaceum was isolated from multiple specimens of sputum , urine, and the abscesses. The patient was treated successfully with the combination of isoniazid, ethambutol, rifampin, and ofloxacin, To our knowledge, this is the first detailed description of an extensivel y disseminated infection due to M. scrofulaceum in an immunocompetent host since the advent of AIDS.