Successful replacements of the superior vena cava (SVC) using autogeno
us saphenous or superficial femoral vein or prosthetic grafts have bee
n previously performed, but the use of allograft for treatment of SVC
syndrome has not been reported. The patient treated by the authors was
a forty-one-year-old woman who presented with severe venous congestio
n of the head and neck caused by fibrosing mediastinitis. In addition,
she had sclerosing cholangitis and chronic liver failure. To treat he
r SVC syndrome and provide access for fluid and blood transfusion and
for possible venovenous bypass, SVC reconstruction was performed conco
mitant to orthotopic liver transplantation. A left innominate vein-rig
ht atrial bypass was inserted using an iliocaval allograft. The patien
t had an uncomplicated recovery, and at six months after surgery her S
VC allograft is widely patent and her transplanted liver is functionin
g well. The venous allograft is an excellent conduit for those patient
s who are receiving immunosuppression therapy to avoid rejection of a
transplanted organ.