Sr. Lucas et al., RELATIONSHIP BETWEEN BLOOD LEAD AND NUTRITIONAL FACTORS IN PRESCHOOL-CHILDREN - A CROSS-SECTIONAL STUDY, Pediatrics, 97(1), 1996, pp. 74-78
Objective. The purpose of this study was to assess the relationships b
etween selected nutritional factors and blood lead levels of preschool
children. Methodology. Data on 296 children, aged 9 to 72 months, who
were cared for at the University of Maryland at Baltimore Pediatric A
mbulatory Center were examined in this cross-sectional study. Nutritio
nal status, socioeconomic aspects, medical history, and potential sour
ces of lead exposure were assessed. Blood samples were evaluated for l
evels of blood lead, serum iron (ferritin), free erythrocyte photoporp
hyrin, calcium, and hematocrit. Results. The average blood lead level
was 11.4 mu g/dL. Multicollinearity of nutritional factors was address
ed using regression techniques. After adjusting for confounders, signi
ficant positive associations with blood lead were found for total calo
ric intake (P = .01) and dietary fat (P = .05). Conclusions. The findi
ngs of this study suggest that even when behavioral and environmental
exposures to lead were statistically controlled, total caloric intake
and dietary fat each had an independent and significant association wi
th the level of blood lead.