New indications have recently appeared for cardiac pacing with haemody
namic and antiarrhythmic objectives without any symptomatic bradycardi
a. The best documented indication, though relatively rare, is stimulat
ion of obstructive hypertrophic cardiomyopathy; initially reserved for
cases with favorable results of an acute haemodynamic test, it is now
used in other cases without this criterion; hypertrophic cardiomyopat
hy without permanent obstruction, atrial fibrillation or left bundle b
ranch block. The improvement observed during follow-up is always great
er as a real remodeling of the myocardium seems to occur with ventricu
lar dilatation and/or septal thinning. However, the position of the at
rial, and above all, of the ventricular pacing catheters is critical a
s is regulation of the pacemaker which should allow complete ventricul
ar capture with an AV delay allowing good filling. The follow-up of th
ese patients must therefore be regular and the effects on longevity ar
e unknown. DDD pacing has also been proposed in dilated cardiomyopathy
. The results are contradictory and only very selected cases with left
bundle branch block and long PR interval seem justified with, again,
optimisation of the pacing sites with high septal or biventricular sti
mulation. Recurrent atrial tachycardia, special algorithms preventing
extrasystoles have been tried with variable results. In cases with int
eratrial block, atrial resynchronisation by bi-atrial stimulation has
been assessed with promising results but many technical problems remai
n unsolved.