NEONATAL THROMBOCYTOPENIA CAUSED BY PASSIVE TRANSFER OF ANTI-PL(A1) ANTIBODY BY BLOOD-TRANSFUSION

Citation
C. Marzich et al., NEONATAL THROMBOCYTOPENIA CAUSED BY PASSIVE TRANSFER OF ANTI-PL(A1) ANTIBODY BY BLOOD-TRANSFUSION, The Journal of pediatrics, 128(1), 1996, pp. 137-139
Citations number
10
Categorie Soggetti
Pediatrics
Journal title
ISSN journal
00223476
Volume
128
Issue
1
Year of publication
1996
Pages
137 - 139
Database
ISI
SICI code
0022-3476(1996)128:1<137:NTCBPT>2.0.ZU;2-7
Abstract
A premature male infant with hyaline membrane disease received a 34 ml transfusion of packed erythrocytes from a CPDA1 blood unit on day 2 w ith no adverse consequences. On day 34 he was given a transfusion, and the platelet count decreased. Intravenous immune globulin therapy was initiated and the platelet count steadily increased. Human leukocyte (HLA) antigen and platelet antibody testing showed that the thrombocyt openia was due to passive transfer of platelet-specific antibody from the blood donor.