C. Marzich et al., NEONATAL THROMBOCYTOPENIA CAUSED BY PASSIVE TRANSFER OF ANTI-PL(A1) ANTIBODY BY BLOOD-TRANSFUSION, The Journal of pediatrics, 128(1), 1996, pp. 137-139
A premature male infant with hyaline membrane disease received a 34 ml
transfusion of packed erythrocytes from a CPDA1 blood unit on day 2 w
ith no adverse consequences. On day 34 he was given a transfusion, and
the platelet count decreased. Intravenous immune globulin therapy was
initiated and the platelet count steadily increased. Human leukocyte
(HLA) antigen and platelet antibody testing showed that the thrombocyt
openia was due to passive transfer of platelet-specific antibody from
the blood donor.