PRODUCTION OF INTERLEUKIN-5 AND THE SUPPRESSIVE EFFECT OF CYCLOSPORINE-A IN CHILDHOOD SEVERE ATOPIC-DERMATITIS

Authors
ISHII E YAMAMOTO S SAKAI R HAMASAKI Y MIYAZAKI S
Citation
E. Ishii et al., PRODUCTION OF INTERLEUKIN-5 AND THE SUPPRESSIVE EFFECT OF CYCLOSPORINE-A IN CHILDHOOD SEVERE ATOPIC-DERMATITIS, The Journal of pediatrics, 128(1), 1996, pp. 152-155
Citations number
16
Categorie Soggetti
Pediatrics
Journal title
The Journal of pediatrics → ACNP
ISSN journal
00223476
Volume
128
Issue
1
Year of publication
1996
Pages
152 - 155
Database
ISI
SICI code
0022-3476(1996)128:1<152:POIATS>2.0.ZU;2-F
Abstract
A child with severe atopic dermatitis had marked improvement with oral cyclosporin A (CyA) therapy. The function of activated T lymphocytes and serum interleukin-5 concentrations were reduced, The expression an d production of interleukin-5 were high, but were suppressed during Cy A therapy and by CyA in vitro. Oral CyA therapy may be useful for seve re atopic dermatitis.