DISTRIBUTION OF COPPER IN BIOPSIED CANINE LIVER

Authors
KAWAMURA M WASHIZU T ISHIDA T TOMODA I
Citation
M. Kawamura et al., DISTRIBUTION OF COPPER IN BIOPSIED CANINE LIVER, Experimental animals, 45(1), 1996, pp. 85-88
Citations number
10
Categorie Soggetti
Veterinary Sciences",Zoology
Journal title
Experimental animals → ACNP
ISSN journal
13411357
Volume
45
Issue
1
Year of publication
1996
Pages
85 - 88
Database
ISI
SICI code
1341-1357(1996)45:1<85:DOCIBC>2.0.ZU;2-A
Abstract
Biopsied canine liver tissues were investigated histochemically by ele ctron microscopy to demonstrate copper localization. The samples were fixed and stained with the modified sulfide-silver method with a combi nation of iron and zinc removal. Using this method, the hepatic copper , even at a low concentration of 30 mu g/g dry weight, was detectable. Copper was found in the hepatocyte lysosomes or in the cytoplasm as e lectron-dense granules.