M. Ouali et al., ABOUT THE LARGE FLUCTUATIONS OBSERVED USING GAS-PHASE MOLECULAR-DYNAMICS IN THE K-RAS GENE CONTAINING A MISMATCH, Biochimie, 77(11), 1995, pp. 835-839
We describe how we can reduce the periodic bending motions in the simu
lation in vacuo of the molecular dynamics of a short DNA fragment cont
aining the Gly 12 hot spot of the K-ras oncogene and having at its cen
ter a mismatch CA(+).