OCULAR LARVA MIGRANS AND HISTOPATHOLOGICAL LESIONS IN MICE EXPERIMENTALLY INFECTED WITH BAYLISASCARIS-TRANSFUGA EMBRYONATED EGGS

The ability of Baylisascaris transfuga larvae to cause ocular larva mi grans (OLM) in mice was examined. Mice were given approximately 3500 i nfective eggs of B. transfuga per os. Their eyes were removed and exam ined either microscopically or histologically at various intervals pos t-infection. Larvae were recovered beginning 7 days after infection. H istologically, free larvae were observed in the posterior chamber and within the ocular membranes. Larval granulomas were present in the cho roid with involvement of retinal layers. It was concluded that B. tran sfuga larvae have the ability to produce OLM in mice following oral in fection and should be considered as possible agents of OLM in other an imals and in human beings.