Pg. Walker et al., 3-DIMENSIONAL RECONSTRUCTION OF THE FLOW IN A HUMAN LEFT-HEART BY USING MAGNETIC-RESONANCE PHASE-VELOCITY ENCODING, Annals of biomedical engineering, 24(1), 1996, pp. 139-147
Intraventricular flows have been correlated with disease and are of in
terest to cardiologists as a possible means of diagnosis. This study e
xtends a method that use magnetic resonance (MR) to measure the three-
dimensional nature of these flows. Four coplanar, sagittal MR slices w
ere located that spanned the left ventricle of a healthy human. All th
ree velocity components were measured in each slice and 18 phases were
obtained per beat. With use of the MR magnitude images, masks were cr
eated to isolate the velocity data within the heart. These data were r
ead into the software package, Data Visualizer, and the data from the
four slices were aligned so as to reconstruct the three-dimensional vo
lume of the left ventricle and atrium. By representing the velocity in
vectorial form, the three-dimensional intraventricular flow field was
visualized. This revealed the presence of one large line vortex in th
e ventricle during late diastole but a more ordered flow during early
diastole and systole. In conclusion, the use of MR velocity acquisitio
n is a suitable method to obtain the complex intraventricular flow fie
lds in humans and may lead to a better understanding of the importance
of these flows.