Reactivity of -(2-formyl-1H-pyrrol-1-yl)-3-thiophenecarbonitrile and o
f 2-(2-formyl-1H-pyrrol-1-yl)-3-thiophenecarboxamide was evaluated aga
inst various alkoxides. The synthetic pathways involved in these react
ions which led to new 4- and 6-alkoxypyrrolothieno[1,4]diazepines are
described.