CENTRAL-NERVOUS-SYSTEM GRANULOCYTIC SARCOMA IN A PATIENT WITH ESSENTIAL THROMBOCYTHEMIA

Authors
GRANDE M
Citation
M. Grande, CENTRAL-NERVOUS-SYSTEM GRANULOCYTIC SARCOMA IN A PATIENT WITH ESSENTIAL THROMBOCYTHEMIA, American journal of hematology, 51(1), 1996, pp. 64-67
Citations number
24
Categorie Soggetti
Hematology
Journal title
American journal of hematology → ACNP
ISSN journal
03618609
Volume
51
Issue
1
Year of publication
1996
Pages
64 - 67
Database
ISI
SICI code
0361-8609(1996)51:1<64:CGSIAP>2.0.ZU;2-G
Abstract
We report a rare case of central nervous system granulocytic sarcoma ( GS) in a patient with essential thrombocythemia (ET). The diagnosis of GS was established by morphological and cytochemical findings (peroxi dase and naphthol-AS-D-chloroacetate esterase positivity) of neoplasti c cells. GS was detected as an intracranial frontal mass 7 months befo re the transformation of ET in acute myeloid leukemia and relapsed as two extradural spinal masses during the course of leukemic evolution. (C) 1996 Wiley Liss, Inc.