H. Roos et al., OSTEOARTHRITIS OF THE KNEE AFTER INJURY TO THE ANTERIOR CRUCIATE LIGAMENT OR MENISCUS - THE INFLUENCE OF TIME AND AGE, Osteoarthritis and cartilage, 3(4), 1995, pp. 261-267
The degree of cartilage changes by arthroscopic and radiologic examina
tion was evaluated in a retrospective, cross-sectional study of 1012 p
atients with knee complaints at different times after knee injury. Pat
ients were classified by age, sex, trauma date and type of injury. The
condition of the cartilage was graded on a 1-10 scale based on findin
gs at arthroscopy and on weight-bearing radiographs. Patients with inj
ury to the anterior cruciate ligament (isolated or combined with injur
y to meniscus or collateral ligaments) showed the first radiologic sig
ns (joint space narrowing) of osteoarthritis (OA) at an average age of
about 40 years, while patients with isolated meniscus injury had the
same stage of disease at an average age of about 50 years. Both study
groups displayed the first radiologic signs of OA on average about 10
years after the injury and showed increasingly serious arthroscopic an
d radiologic signs of joint damage with increased time between injury
and examination. For patients who sustained an isolated meniscus injur
y between the ages of 17 and 30, the average time until development of
radiologic signs of OA was about 15 years, while for those who had th
e same injury over the age of 30, the corresponding time interval was
only about 5 years. We conclude from this that knee OA becomes increas
ingly severe with increased time between joint injury and examination.
OA changes appear sooner in older patients with knee injury than in t
he young.