NEURODEPRESSING HORMONE (NDH) - FACT OR FICTION

Authors
HUBERMAN A
Citation
A. Huberman, NEURODEPRESSING HORMONE (NDH) - FACT OR FICTION, Crustaceana, 69, 1996, pp. 1-18
Citations number
71
Categorie Soggetti
Zoology,"Marine & Freshwater Biology
Journal title
Crustaceana → ACNP
ISSN journal
0011216X
Volume
69
Year of publication
1996
Part
1
Pages
1 - 18
Database
ISI
SICI code
0011-216X(1996)69:<1:NH(-FO>2.0.ZU;2-B
Abstract
Extracts of the crustacean eyestalk, and particularly of the sinus gla nd, produce an inhibition of the spontaneous firing rate of motor and sensitive neurons in two different bioassays. This activity can be asc ribed to a molecule of low molecular weight, neutral, non-peptidic, so luble in water and methanol, thermostable, different from GABA but sup pressed by picrotoxin. Its nature remains to be elucidated.