Seven indole alkaloids have been isolated from the cultured cyanophyte
Hapalosiphon laingii. In addition to the known metabolites 12-epi-hap
alindole E isonitrile [1], 12-epi-hapalindole C isonitrile [2], hapali
ndolinone A [3], and hapalindolinone B [4], H. laingii contains three
new hapalindoles, 12-epi-hapalindole H [5], 12-epi-hapalindole G [6],
and 12-epi-hapalindole Q isonitrile [7], the structures of which were
elucidated by interpretation of their spectral data.