To investigate the pattern and prevalence of membranous fat necrosis o
f the breast we examined 25 breast biopsies or mastectomy specimens pe
rformed for recurrent lumps following conservative surgery and radiati
on therapy, In addition, we examined 41 consecutive cases taken from o
ur files coded as fat necrosis which were associated with several aeti
ologies, Our results demonstrate that membranous fat necrosis of the b
reast occurs in association with several aetiologies but in its florid
form is most often due to radiation therapy.