Mf. Saettone et al., CONTROLLED-RELEASE OF TIMOLOL MALEATE FROM COATED OPHTHALMIC MINI-TABLETS PREPARED BY COMPRESSION, International journal of pharmaceutics, 126(1-2), 1995, pp. 79-82
Ophthalmic inserts (denominated mini-tablets, MT) for sustained releas
e of timolol were prepared by a standard compression and coating techn
ique. An adequate control of the in vitro drug release from the device
s could be obtained by adjusting the type and amount of acrylic polyme
r coating.