Lr. Pistorius et al., SCREENING FOR ANEMIA IN PREGNANCY WITH COPPER-SULFATE DENSITOMETRY, International journal of gynaecology and obstetrics, 52(1), 1996, pp. 33-36
Objective: The copper sulfate method of screening for anemia was evalu
ated to determine its accuracy in antenatal patients. Method: In an an
tenatal clinic in a tertiary referral center, which also serves a loca
l urban black community, 100 antenatal patients were prospectively tes
ted for anemia by Coulter hemoglobin analysis in comparison with the c
opper sulfate test. The respective accuracy and costs of the tests wer
e evaluated. Results: Once initial technical difficulties had been ove
rcome, the copper sulfate test proved accurate in detecting a hemoglob
in level < 10 g% in pregnancy (sensitivity 94%, specificity 95%, posit
ive predictive value 80%, negative predictive value 99%). The cost of
the copper sulfate test is estimated to be less than 0.3% that of the
Coulter test. Conclusion: The copper sulfate test is accurate and inex
pensive, and can be recommended for screening for anemia in pregnancy.