Severe subjective and physiological sleepiness occur in night work, af
flict almost all individuals and are associated with a performance imp
airment severe enough to explain night-work accident data. The alertne
ss deficit is caused by the displacement of work to the circadian phas
e which is least conducive to alert behaviour, by extension of the tim
e spent awake and by the reduction of sleep length (due to circadian i
nterference with sleep). Sleepiness will be extreme when the three cau
ses are operative simultaneously. The three factors may be used quanti
tatively to predict sleepiness.