SYNTHESIS AND ANTI-HSV-1 ACTIVITY OF NEW 3-AMINO-3-ARYLPROPIONIC ACID-ESTERS

Authors
GUILLON J DALLEMAGNE P RAULT S AMOROS M BOUSTIE J ROBBA M
Citation
J. Guillon et al., SYNTHESIS AND ANTI-HSV-1 ACTIVITY OF NEW 3-AMINO-3-ARYLPROPIONIC ACID-ESTERS, Antiviral chemistry & chemotherapy, 7(1), 1996, pp. 1-6
Citations number
9
Categorie Soggetti
Biology,"Pharmacology & Pharmacy
Journal title
Antiviral chemistry & chemotherapy → ACNP
ISSN journal
09563202
Volume
7
Issue
1
Year of publication
1996
Pages
1 - 6
Database
ISI
SICI code
0956-3202(1996)7:1<1:SAAAON>2.0.ZU;2-#
Abstract
A number of 3-methylbut-2-enyl esters of various 3-amino-3-arylpropion ic acids have been synthesized and tested for antiviral activity again st HSV-1. Many of these compounds, analogues of the 3-methylbut-2-enyl caffeate, isolated from poplar buds, show marked anti-HSV-1 activity and are less toxic than the natural ester.