For the first time porous silicon has been investigated for the purpos
e of application as a substrate material for potentiometric biosensors
operating in aqueous solutions. Porous silicon was prepared from diff
erently doped silicon substrates by a standard anodic etching process.
After oxidation, penicillinase, an enzyme sensitive to penicillin, wa
s bound to the porous structure by physical adsorption. To characteriz
e the electrochemical properties of the so build up penicillin biosens
or, capacitance-voltage (C-V) measurements were performed on these fie
ld-effect structures.