SERUM ENZYME-ACTIVITIES IN INDIVIDUALS WITH DIFFERENT LEVELS OF PHYSICAL-FITNESS

Serum creatine phosphokinase (CPK), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) activities were assayed in 15 healt hy but untrained subjects (US) and seven Olympic rowers (OR). Blood sa mples were obtained at rest, and five and 60 minutes after an ergomete r test, during which cardiorespiratory data were obtained. OR demonstr ated higher resting CPK (p < 0.001) and AST (p < 0.05) levels than the US. CPK and AST reached their highest levels five minutes after the e nd of the ergometer test in both groups, whilst peak ALT was reached f ive and 60 minutes post-test in the US and OR respectively. Fitness pa rameters and serum enzyme levels were better correlated in the OR grou p. it is concluded that: (1) exercise temporarily increases the activi ties of serum AST, ALT, and CPK, (2) increased physical fitness has no bearing on resting serum ALT enzyme levels, although this was not the case with AST and CPK, and (3) exercise duration rather than fitness levels seems to be related to serum CPK, AST, and ALT activities.