THE PULMONARY TOXICITY OF CINNAMON DUST IN RATS

The histopathological effect of a single intratracheal dose of respira ble cinnamon dust, cinnamon dust extract, and cellulose dust on the lu ngs of rats was studied sequentially one, seven days and one month aft er treatment. Exposure to respirable cinnamon and cellulose dusts resu lted in alveobronchiolitis at the end of the first and seventh day, an d fibrotic changes by the end of the first month. As the extract of ci nnamon dust caused no histopathological alterations, it is assumed tha t the cellulose content of cinnamon dust was responsible for the histo logical reactions.