AMADORI REARRANGEMENT OF N-GLUCOSIDES OF 6-SUBSTITUTED 3-AMINO-2-ARYL-4(3H)-QUINAZOLINONES

Authors
SALEH MA ABDO MA ABDELMEGEED MF ELHITI GA
Citation
Ma. Saleh et al., AMADORI REARRANGEMENT OF N-GLUCOSIDES OF 6-SUBSTITUTED 3-AMINO-2-ARYL-4(3H)-QUINAZOLINONES, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 35(2), 1996, pp. 147-150
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry → ACNP
ISSN journal
03764699
Volume
35
Issue
2
Year of publication
1996
Pages
147 - 150
Database
ISI
SICI code
0376-4699(1996)35:2<147:ARONO6>2.0.ZU;2-U
Abstract
Amadori rearrangement of N-glucosides of 6-substituted 3-amino-2-aryl- 4(3H)-quinazolinones has been carried out by the condensation of equim olecular amounts of D-glucose and oxalate of 6-substituted 3-amino-2-a ryl-4-(3H)-quinazolinones (1a-f) in boiling methanol. These compounds can also be obtained by heating the N-glucosides of 6-substituted 3-am ino-2-aryl-4(3H)-quinazolinones (2a-f) in absolute methanol in the pre sence of dry oxalic acid. The products obtained are characterized by I R, 1(H) NMR, C-13 NMR and mass spectral data and elemental analyses.