EFFECT OF TEMPERATURE ON THE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC SEPARATION OF THE ANTI-HIV AGENTS, DIDANOSINE AND STAVUDINE

Authors
STANCATO FA SRINIVAS NR KNUPP CA
Citation
Fa. Stancato et al., EFFECT OF TEMPERATURE ON THE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC SEPARATION OF THE ANTI-HIV AGENTS, DIDANOSINE AND STAVUDINE, BMC. Biomedical chromatography, 10(1), 1996, pp. 29-31
Citations number
9
Categorie Soggetti
Chemistry Analytical","Pharmacology & Pharmacy",Biology,"Biochemical Research Methods
Journal title
BMC. Biomedical chromatography → ACNP
ISSN journal
02693879
Volume
10
Issue
1
Year of publication
1996
Pages
29 - 31
Database
ISI
SICI code
0269-3879(1996)10:1<29:EOTOTH>2.0.ZU;2-C
Abstract
This paper examines the effect of temperature on the chromatographic s eparation characteristics of anti-HIV agents, didanosine and stavudine . As a result of lowering the column temperature, an improved resoluti on between didanosine and stavudine peaks is observed. Thus, lower tem peratures may permit the simultaneous monitoring of didanosine and sta vudine levels.