Blood loss from split-thickness skin graft donor sites may be signific
ant, various topical agents have been used to decrease this blood loss
, including thrombin and epinephrine solutions of varying concentratio
ns, We describe a K-Y jelly/epinephrine mixture that serves both as a
lubricant for the dermatome and as a hemostatic agent, This mixture, i
n comparison with other topical agents, produces rapid hemostasis and
offers the advantages of easy use, ready availability, and low cost, T
he blood loss savings based on this hemostatic technique is quantifiab
le and significant.