HIGHLY EFFICIENT AND DIASTEREOSELECTIVE APPROACHES TO (-GRANDISOL AND(-)-GRANDISOL())

(+)-Grandisol, (+)-1, was isolated for the first time in 1969 by Gueld ner et al.(1) it is the most important constituent of the aggregation male-produced pheromone of the cotton boil weevil, Anthonomous grandis Boheman, a Curculionidae being an important pest of the cotton boll.( 2) Morever, (+)-grandisol is also released by females of the ambrosia beetle Trypodendron signatum L.,(3) by males of bark beetles Pityophth orus pityographus,(4) and other insects like Pityogenes quadridens,(5) Pityogenes calcaratus(5) and also by the genus Pissodes.(6)