Wound infection is of great concern following coronary artery bypass g
raft surgery (CABG). A rapidly applied, 1-step iodophorin-alcohol, wat
er-insoluble solution (experimental) was compared with the traditional
2-step aqueous iodophor 5- to 10-minute scrub and paint (control) in
200 consecutive CABG patients. The experimental solution took less tim
e to apply in the operating room, lasted significantly longer on the i
ncised wound edge at closure, and significantly improved incise drape
adhesion during surgery. The overall infection rate was not significan
tly different between the 2 groups, but there was a trend of lower inf
ection rates with the newer product, especially in elderly and diabeti
c patients.