21 seroconversional HIV-infected subjects have been examined. 16 of th
em presented with acute symptoms. The disease in tile period of seroco
nversion manifested with fever, weakness, headache, pain in tile throa
t, enlargement of peripheral lymph nodes, polymorphous eruption. Typic
al mononucleosis-like syndrome occurred in 3 patients only. Half of th
e patients had subclinical disease, no emption was seen. Because of cl
inical indications only 8 of 21 patients were examined for HIV infecti
on. One-third of the patients in seroconversion had moderate thrombocy
topenia, probably of autoimmune nature. Autoimmune disorder of the thy
roid was registered in 1 patient. nle diagnosis of acute HIV infection
is not easy in view of rare occurrence of immunodeficiency typical fo
r this infection. Candidiasis of the mucosa was seen in 37.5%, low lev
els of CD4-lymphocytes in 66.7% of the cases.