WEST SYNDROME IN TUBEROUS SCLEROSIS

Observation's analysis of 5 children in age from 9 months to 4 years 1 1 months with tuberous sclerosis was performed. The initial manifestat ions of disease were following: early children form of epilepsy exactl y infantile spasms (West syndrome) appearance, dermal alterations in t he form of depigmented spots as well as unprogressive delay in psychov erbal development. Together with clinical symptoms the main criterion in early form of tuberous sclerosis diagnosis determination turned out to be brain's specific alterations (tuberses) which were revealed by computer tomography. The correlation was observed between epileptic se izures polymorphism and frequency as well as brain's morphological alt erations. Derivatives of valproic acid were the basic drugs in treatme nt of epileptic seizures in patients.